Table 1.
Mitochondrial respiratory chain activities in skeletal muscle
| Enzyme | Values | Controls (mean ± SD)a |
|---|---|---|
| Citrate synthase (CS) | 570.5b | 550 ± 350 |
| Complex I (NADH:ubiquinone oxidoreductase) | 8.4 c | 15.9 ± 5.9 |
| Complex II (succinate:ubiquinone oxidoreductase) | 5.5c | 12.5 ± 8.0 |
| Complex III (ubiquinol:ferricytochrome-c oxidoreductase) | 27.8 c | 68.8 ± 37.8 |
| Complex IV (ferrocytochrome-c:oxygen oxidoreductase) | 29.0 c | 66.5 ± 36.6 |
The values in bold indicate an abnormal activity value
aSkeletal muscle from healthy control people: N = 14
bIn SA (SA is specific activity: nmol × min−1 × mg protein−1)
cIn (SA of Complex/SA of Citrate Synthase) × 100