Fig. 4.

ADMIXTURE analysis. Results with K = 5 hypothetical ancestries are shown. Each column represents one individual. Individuals with [GJB2:c.71G>A;p.(Trp24*)] and [MANBA:c.2158-2A>G] variants are labeled. Ten random individuals from each of the five main 1000 Genome ancestries are also plotted for comparison purposes. PJL (Punjabi) were chosen to represent SAS as North-Western Indian populations play an important role in the South Asian ancestry component of Roma [33]. Populations codes: ROMA: Romani hearing-impaired family members included in this study, AFR: African; AMR: Admixed American (Latinos); EAS: East Asian; EUR: European; SAS: South Asian. Subpopulations: CHB: Han Chinese in Beijing, China; GBR: British in England and Scotland; PEL: Peruvians from Lima, Peru; PJL: Punjabi from Lahore, Pakistan; YRI: Yoruba in Ibadan, Nigeria