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. Author manuscript; available in PMC: 2019 Oct 4.
Published in final edited form as: Science. 2019 Feb 1;363(6426):538–542. doi: 10.1126/science.aau8722

Fig. 2. DRN 5-HT neural activity increases upon movement in high-threat environments.

Fig. 2.

(A) TST schematic. (B) Example TST photometry from the Fig. 1 mouse. GCaMP ΔF/F in black, movement in red. (C) Mean ΔF/F aligned to TST movement onset. (D) Mean ΔF/F before and after TST movement onset in GCaMP (n=8) and GFP (n=2) mice. (E) Mean ΔF/F aligned to escape movement onset during failed avoidance trials. (F) Mean ΔF/F before and after escape movement onset in GCaMP (n=7) mice. *P < 0.05, **P < 0.01, Wilcoxon signed-rank test. Error bars indicate s.e.m.