Table 3.
Circuit characteristics by patient weight
| Characteristic | Group 1 (Weight <10 kg), n=711 | Group 2 (Weight 10–20 kg), n=66 | Group 3 (Weight >20 kg), n=107 |
|---|---|---|---|
| Blood flow rate, ml/min | 40 (30, 40) | 40 (30, 40) | 40 (40, 40) |
| Cardiorespiratory support at initiation (or with complications at initiation) | 24 (3) | 4 (7) | 0 |
| Type of support neededa | |||
| Normal saline | 4 | 1 | — |
| Inotrope | 8 | — | — |
| Calcium chloride | 1 | 2 | — |
| Albumin | 8 | 1 | — |
| Sodium bicarbonate | 2 | — | — |
| Blood transfusion | 5 | ||
| Circuits with complications during therapy | 106 (15) | 12 (18) | 15 (14) |
| Type of complicationa | |||
| Hypothermia | 4 | — | — |
| Bleeding | 17 | — | — |
| Hypotensionb | 30 | 3 | 4 |
| Clot | 37 | 9 | 6 |
| Thrombocytopenia | 2 | — | — |
| Seizure | — | — | 2 |
| Catheter malfunction | 12 | — | — |
| Other | 8 | — | 3 |
| Anticoagulation | |||
| Heparin | 616 | 47 | 68 |
| Citrate | 2 | — | — |
| Argatroban | 0 | 11 | 3 |
| None | 91 | 5 | 30 |
| Unknown/other | 2 | 3 | 6 |
Continuous variables are shown as median (interquartile range) and categorical data as number (%). —, zero.
a
Some patients needed more than one intervention or had multiple complications.
b
Hypotension was defined as needing bolus of fluid, new inotrope requirement, or an increase in rate of existing inotrope infusion.