Table 2.
Plasma AgRP, IGF-1, Sex, Age, and BMI for Patients With Acromegaly (Surgery and Pegvisomant Groups Combined) vs Matched Healthy Subjects
| Variable | Acromegaly Before Treatment | Matched Healthy Subjects | P Value | Acromegaly After Treatment | Matched Healthy Subjects | P Value |
|---|---|---|---|---|---|---|
| Plasma AgRP, pg/mL | 100 (78–139) | 62.9 (58–67) | < 0.0001 | 66 (59–83) | 63 (57–70) | 0.08 |
| IGF-I, µg/L | 600 (499–735) | 142.3 (132–159) | < 0.0001 | 228 (182–312) | 145 (134–158) | < 0.0001 |
| Sex, n | NA | NA | ||||
| Male | 14 | 42 | 14 | 42 | ||
| Female | 9 | 27 | 9 | 27 | ||
| Age, y | 44.1 (22–62) | 44.8 (22–61.7) | 0.68 | 45 (21–64) | 45.3 (24–61.7) | 0.39 |
| BMI, kg/m2 | 29.6 (27.6–33) | 29.1 (27.8–32) | 0.22 | 29 (26.6–33) | 29 (27.8–32) | 0.32 |
Data presented as median (interquartile range), unless otherwise specified.
Abbreviation: NA, not applicable.