Table 4.
LN18 Cell Lines. Sensitivity and Specificity for Predicting Isocitrate Dehydrogenase (IDH) Mutation Using PC-Linear Discriminant Analysis for Different Sample Preparation Methods Using Spectra From Individual Cell Line Batches and Combined Batches
| Preparation method, cell line | Sensitivity | Specificity | Accuracy |
|---|---|---|---|
| Cryosection, 1 | 0.85 | 0.70 | 0.82 |
| Cryosection, 2 | 0.91 | 0.99 | 0.98 |
| Cryosection, combined | 0.78 | 0.55 | 0.66 |
| FFPE, 1 | 0.99 | 0.99 | 0.99 |
| FFPE, 2 | 0.83 | 0.85 | 0.92 |
| FFPE combined | 0.95 | 0.89 | 0.97 |
FFPE = formalin-fixed paraffin-embedded.