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. 2019 Sep 24;44(5):1908–1920. doi: 10.3892/ijmm.2019.4350

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Copyright: © Yang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Protein expression of lipid metabolism-associated genes in the liver of the NFD groups. (A) The expression of hepatic lipase, HNF4α, ABCG5, CD36, FASN, HMGCoAR, SCD-1 proteins was detected by western blotting. (B) The relative protein levels of hepatic lipase, HNF4α, ABCG5, CD36, FASN, HMGCoAR and SCD-1. The results are presented as the mean ± standard deviation. n=6. ^**P<0.01, ^***P<0.001 vs. NFD-CON. NFD-CON, control fed with NFD; NFD-AL, mice fed with NFD and treated with a low dose of DADS; NFD-AH, mice fed with NFD and treated with a high dose of DADS. NFD, normal food diet; DADS, diallyl disulfide; HNF4α, hepatocyte nuclear factor 4α; ABCG5, adenosine triphosphate-binding cassette subfamily G members 5; FASN, fatty acid synthase; HMGCoAR, hydroxy-methyl-glutaryl coenzyme A reductase; SCD1, Stearoyl-CoA desaturase-1.