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. 2019 Sep 5;44(5):1753–1770. doi: 10.3892/ijmm.2019.4332

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Copyright: © Xu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Identification of DEGs between skin samples from healthy control individuals and patients with SSc. (A) A volcano plot showing the difference between SSc and control skin samples after analysis of the GSE95065 dataset with GEO2R. The X-axis represents the fold-change (log-scaled) and the Y-axis represents the P-value (log-scaled). Each symbol represents a different gene. The red symbols represent upregulated genes; green symbols represent downregulated genes. (B) A volcano plot of the GSE76885 dataset. (C) A Venn diagram showing that 106 genes are shared by both the GSE95065 and the GSE76885 datasets. SSc, systemic sclerosis; DEG, differentially expressed genes.