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. 2019 Sep 17;44(5):1677–1686. doi: 10.3892/ijmm.2019.4344

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Copyright: © Bao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effects of incremental load training on the expression of MKK3, p-MKK3 p38MAPK and p-p38MAPK in the kidney tissues of aged mice. (A) Western blot analysis was used to determine changes in the protein expression of p-MKK3/MKK3 and p-p38MAPK/p38MAPK in the three groups. Bar graphs show the relative quantification of (B) p-MKK3/MKK3 and (C) p-p38MAPK/p38MAPK. Values are expressed as the mean ± standard deviation (n=3). ^*P<0.05, ^**P<0.01. YC, young control group; OC, elderly control group; OY, elderly exercise group; MAPK, mitogen-activated protein kinase; MKK, MAPK kinase; p-, phosphorylated.