Table 3. The hazard ratio of associated factors for cardiovascular outcomes.
| four-point MACEs | CVD-death | |||||||
|---|---|---|---|---|---|---|---|---|
| Characteristics | Univariable | Multivariable | Univariable | Multivariable | ||||
| HR (95% CI) | P value | HR (95% CI) | P value | HR (95% CI) | P value | HR (95% CI) | P value | |
| Lowest relative CD34+ tertile vs. medium+highest tertiles | 2.24 (1.42–3.52) | 0.001* | 1.80 (1.08–2.99) | 0.023* | 3.63 (1.93–6.86) | <0.001* | 2.50 (1.23–5.10) | 0.011* |
| Male gender | 1.21 (0.76–1.92) | 0.424 | 1.12 (0.65–1.93) | 0.683 | 1.01 (0.54–1.89) | 0.979 | 1.00 (0.47–2.14) | 0.991 |
| Age-per 10 years | 1.01(0.99–1.03) | 0.178 | 1.00 (0.98–1.03) | 0.948 | 1.39 (1.03–1.87) | 0.030* | 0.99 (0.96–1.03) | 0.748 |
| Dialysis-vintage (year) | 1.01 (0.98–1.04) | 0.443 | - | - | 1.02 (0.97–1.06) | 0.489 | - | - |
| Diabetes | 1.56 (1.99–2.46) | 0.058 | 1.18 (0.71–1.97) | 0.526 | 1.28 (0.69–2.41) | 0.437 | 1.03 (0.50–2.15) | 0.930 |
| Hypertension | 1.51 (0.87–2.62) | 0.144 | - | - | 1.46 (0.67–3.19) | 0.337 | - | - |
| Smoking habit | 1.56 (0.97–2.51) | 0.068 | 1.27 (0.72–2.23) | 0.411 | 1.30 (0.66–2.56) | 0.452 | 1.19 (0.53–2.68) | 0.673 |
| History of CVD | 2.77 (1.73–4.44) | < 0.001* | 2.63 (1.22–4.40) | <0.001* | 5.95 (2.82–12.55) | <0.001* | 4.67 (2.07–10.52) | <0.001* |
| Hemoglobin (g/dl) | 0.91 (0.75–1.10) | 0.313 | 0.99 (0.81–1.21) | 0.942 | 0.69 (0.52–0.91) | 0.010* | 0.91 (0.67–1.24) | 0.557 |
| GNRI | 0.99 (0.96–1.02) | 0.451 | 1.01 (0.97–1.05) | 0.614 | 0.92 (0.88–0.97) | 0.002* | 0.96 (0.90–1.01) | 0.125 |
| C-reactive protein (mg/dl) | 1.22 (1.03–1.45) | 0.021* | 1.15 (0.95–1.41) | 0.161 | 1.44 (1.14–1.82) | 0.002* | 1.30 (0.99–1.69) | 0.056 |
| iPTH | 1.00 (0.99–1.00) | 0.145 | 1.00 (0.99–1.00) | 0.744 | 0.99 (0.99–1.001) | 0.289 | 1.00 (0.99–1.00) | 0.821 |
MACEs Major adverse cardiovascular disease, HR hazard ratio, CI confidence interval
*p< 0.05: statistically significant association