Table 4. Adverse maternal and fetal outcomes of women with pre-eclampsia/eclampsia compared to women with chronic/gestational hypertension.
Maternal and fetal outcomes |
Chronic/ Gestational Hypertension N = 170 n (%) |
Pre-eclampsia/ Eclampsia N = 281 n (%) |
Crude RR (95% CI) |
P-value | Adjusted RR (95% CI) |
P-value |
---|---|---|---|---|---|---|
Maternal outcomes | ||||||
Caesarean sectiona | 72 (42.4) | 159 (57.0) | 1.41 (1.06, 1.89) | 0.02 | 1.37 (1.01, 1.87) | 0.04 |
Prolonged maternal hospital stayb | 46 (27.1) | 123 (43.9) | 1.63 (1.15, 2.28) | 0.005 | 1.40 (0.97, 2.03) | 0.07 |
Fetal outcomes | ||||||
Preterm delivery | ||||||
<34 weeksc | 11 (6.5) | 58 (21.3) | 3.26 (1.71, 6.22) | <0.001 | 2.74 (1.40, 5.36) | 0.003 |
<37 weeksd | 36 (21.3) | 111 (40.7) | 1.91 (1.31, 2.78) | 0.001 | 1.89 (1.25, 2.85) | 0.002 |
Low Apgar score (<7) at 1 minutee | 57 (36.5) | 87 (38.7) | 1.06 (0.76, 1.48) | 0.74 | 1.16 (0.82, 1.63) | 0.40 |
Low Apgar score (<7) at 5 minutesf | 11 (7.1) | 26 (11.6) | 1.65 (0.81, 3.33) | 0.17 | 1.66 (0.81, 3.43) | 0.17 |
NICU admissiong | 31 (19.8) | 70 (30.7) | 1.55 (1.02, 2.37) | 0.04 | 1.11 (0.72, 1.71) | 0.64 |
Abortions/Perinatal mortalityh | 19 (11.2) | 65 (23.5) | 2.09 (1.25, 3.48) | 0.01 | 1.07 (0.40, 2.80) | 0.90 |
RR, relative risk; CI, confidence interval; NICU, Neonatal Intensive Care Unit
aAdjusted for stage of pregnancy at admission- risk estimates obtained by exclusion of 2 previous caesarean sections, previous extensive myomectomy and major placenta praevia
bAdjusted for estimated gestational age (EGA) at diagnosis, EGA at delivery and stage of pregnancy at admission
cAdjusted for EGA at diagnosis, number of antenatal visits, and stage of pregnancy at admission
dAdjusted for parity (prior to delivery), EGA at diagnosis; number of antenatal visits, and stage of pregnancy at admission
eAdjusted for mode of delivery
fAdjusted for marital status and mode of delivery
gAdjusted for EGA at delivery, mode of delivery and Apgar score at 5 minutes
hAdjusted for EGA at delivery and Apgar score at 5 minutes.