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. 2019 Oct 4;14(10):e0223478. doi: 10.1371/journal.pone.0223478

Table 4. Adverse maternal and fetal outcomes of women with pre-eclampsia/eclampsia compared to women with chronic/gestational hypertension.

Maternal and fetal outcomes
Chronic/
Gestational
Hypertension
N = 170
n (%)
Pre-eclampsia/
Eclampsia
N = 281
n (%)
Crude RR
(95% CI)
P-value Adjusted RR
(95% CI)
P-value
Maternal outcomes
Caesarean sectiona 72 (42.4) 159 (57.0) 1.41 (1.06, 1.89) 0.02 1.37 (1.01, 1.87) 0.04
Prolonged maternal hospital stayb 46 (27.1) 123 (43.9) 1.63 (1.15, 2.28) 0.005 1.40 (0.97, 2.03) 0.07
Fetal outcomes
Preterm delivery
    <34 weeksc 11 (6.5) 58 (21.3) 3.26 (1.71, 6.22) <0.001 2.74 (1.40, 5.36) 0.003
    <37 weeksd 36 (21.3) 111 (40.7) 1.91 (1.31, 2.78) 0.001 1.89 (1.25, 2.85) 0.002
Low Apgar score (<7) at 1 minutee 57 (36.5) 87 (38.7) 1.06 (0.76, 1.48) 0.74 1.16 (0.82, 1.63) 0.40
Low Apgar score (<7) at 5 minutesf 11 (7.1) 26 (11.6) 1.65 (0.81, 3.33) 0.17 1.66 (0.81, 3.43) 0.17
NICU admissiong 31 (19.8) 70 (30.7) 1.55 (1.02, 2.37) 0.04 1.11 (0.72, 1.71) 0.64
Abortions/Perinatal mortalityh 19 (11.2) 65 (23.5) 2.09 (1.25, 3.48) 0.01 1.07 (0.40, 2.80) 0.90

RR, relative risk; CI, confidence interval; NICU, Neonatal Intensive Care Unit

aAdjusted for stage of pregnancy at admission- risk estimates obtained by exclusion of 2 previous caesarean sections, previous extensive myomectomy and major placenta praevia

bAdjusted for estimated gestational age (EGA) at diagnosis, EGA at delivery and stage of pregnancy at admission

cAdjusted for EGA at diagnosis, number of antenatal visits, and stage of pregnancy at admission

dAdjusted for parity (prior to delivery), EGA at diagnosis; number of antenatal visits, and stage of pregnancy at admission

eAdjusted for mode of delivery

fAdjusted for marital status and mode of delivery

gAdjusted for EGA at delivery, mode of delivery and Apgar score at 5 minutes

hAdjusted for EGA at delivery and Apgar score at 5 minutes.