Fig 1. Regional association plots of two SNVs associated with DIILD.

Upper panel; P values of the SNVs are plotted (as–log₁₀P values) against their physical location on chromosome 22 (A) and 20 (B). The genetic recombination rates estimated from the 1,000 Genomes samples (Japanese in Tokyo, JPT + Chinese in Beijing, CHB) are shown with a blue line. SNV color indicates linkage disequilibrium (LD) with rs35198919 (A) and rs12625311 (B) according to a scale from r² = 0 to 1 based on pairwise r² values from the Asian (ASN) data from the 1,000 Genomes Project. Lower panel; gene annotations from the University of California Santa Cruz genome browser.