Table 1. Patient characteristics.
| Age at diagnosis (years) † | 66 years old [60, 71] | |
| Sex | 370 male, 12 female | |
| Radiologic variables | ||
| Central vs. peripheral | 230 (60.2%) vs. 152 (39.8%) | |
| Obstructive pneumonitis/atelectasis | Yes | 176 (46.1%) |
| No | 206 (53.9%) | |
| Enhancement ratio* | 1.17 ± 0.36 | |
| Heterogeneity (HU)* | 28.57 ± 13.73 | |
| Necrosis or cavitation | None | 246 (64.4%) |
| Necrosis | 112 (29.3%) | |
| Cavitation | 24 (6.3%) | |
| CT-determined lung disease | Normal | 282 (73.8%) |
| Emphysema | 81 (21.2%) | |
| Interstitial lung abnormalities | 19 (5.0%) | |
| Clinical variables | ||
| Bronchoscopic detectabililty | Yes | 239 (62.6%) |
| No | 143 (37.4%) | |
| FEV1 (% PRED)* | 89.7 ± 17.7 | |
| FEV1/FVC (%)* | 53.8 ± 11.4 | |
| Serum CEA (ng/ml)* | 4.52 ± 21.65 | |
| Surgery | Pneumonectomy | 55 (14.4%) |
| Subpneumonectomy | 327 (85.6%) | |
| Adjuvant therapy | Chemotherapy | 228 (59.7%) |
| Radiation therapy | 111 (29.1%) | |
| None | 134 (35.1%) | |
| Histopathologic variables | ||
| Pathologic T status | T1 | 71 (18.6%) |
| T2 | 231 (60.5%) | |
| T3 | 72 (18.9%) | |
| T4 | 8 (2.1%) | |
| Pathologic N status | N0 | 245 (64.1%) |
| N1 | 95 (24.9%) | |
| N2 | 42 (11.0%) | |
| Differentiation | WD | 38 (10.0%) |
| MD | 254 (66.4%) | |
| PD/DD | 90 (23.6%) | |
| Lymph node ratio* | 0.03 ± 0.14 |
CEA, carcinoembryonic antigen; DD, dedifferentiated; FEV1, forced expiratory volume in a second; FVC, forced vital capacity; MD, moderately differentiated; PD, poorly differentiated; WD, well-differentiated. Except where indicated, numbers in parentheses are percentages.
†Data are median values [1st quartile, 3rd quartile].
*Data are mean values ± standard deviation.