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. Author manuscript; available in PMC: 2019 Oct 4.
Published in final edited form as: ACS Infect Dis. 2018 Mar 16;4(4):516–522. doi: 10.1021/acsinfecdis.7b00224

Table 3.

Pharmacokinetics of plasma exposure after oral dosing of PP (top of pair) and PrP (bottom of pair) in BALB/c mice.

Dose (mg/kg) Tmax (min) Cmax (μM) AUC (min*μmol/L) Half-life (min)
6 10 560 7.8 13700 1110
13 10 400 4.9 6400 900
7 10 320 12.8 13700 1190
14 10 480 24.9 27900 930
9 10 50 5.2 770 110
16 25 50 28 8500 100