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. 2019 Oct 4;9:14331. doi: 10.1038/s41598-019-49881-9

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Coverage plots of selected Yfr2, Yfr1 and Yfr10 targets discovered using the CRAFD-Seq approach. Mapped read regions of the Yfr2, Yfr1 and Yfr10 affinity pull-down libraries are coloured in green, blue and dark grey, respectively, and those of the control library are shown in light grey. The orange boxes correspond to gene positions of glgC (encoding glucose-1-phosphate adenyltransferase) and asglgC, gap2 (encoding glyceraldehyde-3-phosphate dehydrogenase), pgk (encoding phosphoglycerate kinase) and pgmI (encoding phosphoglycerate mutase). The numbers in the grey, blue and green boxes correspond to the peak IDs of Yfr10, Yfr1 and Yfr2 listed in Tables S1, S2 and S3, respectively. Boxes coloured in green and white stripes correspond to peak regions where only one of the duplicate libraries was more than 2-fold enriched. White boxes correspond to called peak regions that were not enriched.