Table 1.
Demographic and Clinical Characteristics of the three samples.
| Montreal Healthy controls |
Montreal Patient Controls |
Montreal Suicide Attempters | F/χ² | P | Post-Hoc | ||||
|---|---|---|---|---|---|---|---|---|---|
| n = 38 | n = 20 | n = 16 | |||||||
| Gender, N males (%) | 18 | (47.3) | 6 | (30.0) | 3 | (18.8) | 4.5 | n.s. | |
| Age, mean (SD) | 33.1 | (8.2) | 40.7 | (10.3) | 37.8 | (10.5) | 4.7 | 0.02 | PC > HC |
| BDI score, mean (SD) | 1.7 | (1.7) | 30.1 | (11.9) | 30.5 | (11.5) | 101.8 | <10−3 | PC, SA > HC |
| HDRS score, mean (SD) | 1.2 | (1.7) | 30.1 | (5.5) | 27.3 | (9.4) | 216.9 | <10−3 | PC, SA > HC |
| Age at first depression (SD) | — | — | 38.2 | (11.3) | 29.4 | (9.9) | 5.0 | 0.03 | SA < PC |
| Number of depressive episodes (SD) | — | — | 2.0 | (1.2) | 2.1 | (1.1) | 1.6 | n.s. | |
| Family history of suicidal act, N (%) | — | — | 5 | (25) | 3 | (18.8) | 1.9 | n.s. | |
| Number of suicidal act (SD) | — | — | — | — | 1.4 | (1.3) | — | — | |
| History of violent suicidal act, N (%) | — | — | — | — | 2 | (13.3) | — | — | |
| SIS score (SD) | — | — | — | — | 18.2 | (5.7) | — | — | |
|
History of physical or sexual childhood trauma, N (%) |
— | — | 4 | (20) | 7 | (43.8) | 3.0 | n.s. | |
|
Jena Healthy controls |
Jena Patient Controls |
Jena Suicide Attempters | F/χ² | P | Post-Hoc | ||||
| n = 28 | n = 23 | n = 26 | |||||||
| Gender, N males (%) | 9 | (32.1) | 4 | (17.4) | 7 | (26.9) | 1.5 | n.s. | |
| Age, mean (SD) | 36.7 | (9.0) | 35.1 | (11.3) | 36.8 | (11.1) | 0.2 | n.s. | |
| BDI score, mean (SD) | 1.9 | (2.2) | 31.3 | (8.1) | 25.8 | (13.1) | 81.4 | <10−3 | PC, SA > HC |
| HDRS score, mean (SD) | — | — | 21.5 | (9.4) | 21.7 | (10.4) | 0.003 | n.s. | — |
| Age at first depression (SD) | — | — | 29.2 | (12.6) | 28.3 | (10.3) | 0.08 | n.s. | |
| Number of depressive episodes (SD) | — | — | 1.0 | (0.9) | 2.0 | (2.2) | 4.0 | 0.05 | |
| Family history of suicidal act, N (%) | — | — | 5 | (21.7) | 5 | (19.2) | |||
| Number of suicidal act (SD) | — | — | — | — | 0.3 | (0.7) | |||
| History of violent suicidal act, N (%) | — | — | — | — | 10 | (38.5) | |||
| SIS score (SD) | — | — | — | — | 20.3 | (4.2) | |||
| Antidepressant medication | 1.8 | n.s. | |||||||
| SSRI | 10 | 10 | |||||||
| SNRI | 10 | 9 | |||||||
| SSRI + Quetiapine | 0 | 6 | |||||||
| unmedicated | 3 | 1 | |||||||
|
Montreal Healthy controls |
Montreal Patient relatives |
Montreal Suicide relatives |
F/χ² | P | Post-Hoc | ||||
| n = 38 | n = 16 | n = 16 | |||||||
| Gender, N males (%) | 18 | (47.3) | 7 | (43.8) | 8 | (50.0) | 0.3 | n.s. | |
| Age, mean (SD) | 33.1 | (8.2) | 37.9 | (8.7) | 50.8 | (9.2) | 14.8 | <10−3 | SR > PR, HC |
| BDI score, mean (SD) | 1.7 | (1.7) | 1.7 | (2.2) | 1.9 | (3.1) | 0.4 | n.s. | |
| HDRS score, mean (SD) | 1.2 | (1.7) | 1.8 | (2.3) | 2.3 | (2.0) | 2.1 | n.s. | |
Footnotes: HC: Healthy Controls; PC: Patient Controls; SA: Suicide Attempters; SR: Suicide Relatives; PR: Patient Relatives; SD: Standard Deviation; n.s.: non significant; BDI: Beck Depression Inventory; HDRS: Hamilton Depression Rating Scale; SIS: Beck Suicide Intent Scale; SSRI: Selective Serotonin Receptor Inhibitor; SNRI: Serotonin and Noradrenalin Receptor Inhibitor.