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. 2019 Oct 4;10:4523. doi: 10.1038/s41467-019-12433-w

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Fig. 8 — Renoprotection by ATG is abrogated in diabetic Pod-PP2A^−/− mice. a Schematics of the experimental design. Doxycycline (Dox) was administered in 6-week old Pod-PP2A^−/− mice. Diabetes was induced with STZ at 6 weeks postDox induction. ATG or DMSO vehicle was administered daily starting at 6 weeks post diabetes induction for 8 weeks. All mice were killed 14 weeks after diabetes induction. b Analysis of urinary albumin-to-creatinine ratio (UACR) at week 0 or week 8 of ATG treatment, which were not significant (n.s.) between treatment groups by two-way ANOVA with Tukey’s post hoc analysis. n = 5. c Representative PAS images. Scale bar, 20 μm. d, e Representative immunofluorescence images d and quantification of WT1⁺ cells e are shown per glomerular cross-section. The data are represented as mean ± SD. Two-tailed t test was performed to compare the data between two groups. Source data are provided as a Source Data file