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. 2019 Oct 4;9:14308. doi: 10.1038/s41598-019-50488-3

Table 4.

Crude and multivariate-adjusted ORs (95% CI) for decreased pulmonary function parameters according to BMI.

BMI category Crude OR (95% CI) Multivariate-adjusted OR (95% CI)
Predicted FEV1% < 80%
   Obese 1.00 (reference) 1.00 (reference)
   Normal 0.872 (0.81–0.90) 0.93 (0.90–0.97)
   Underweight 1.77 (1.69–1.85) 2.10 (1.98–2.21)
   P for trend <0.001 <0.001
Predicted FVC% < 80%
   Obese 1.00 (reference) 1.00 (reference)
   Normal 1.58 (1.52–1.64) 1.32 (1.27–1.38)
   Underweight 8.44 (8.04–8.86) 4.90 (4.62–5.18)
   P for trend <0.001 <0.001
FEV1/FVC < 70%
   Obese 1.00 (reference) 1.00 (reference)
   Normal 0.86 (0.81–0.91) 1.14 (1.06–1.23)
   Underweight 0.35 (0.29–0.41) 0.95 (0.75–1.19)
   P for trend <0.001 0.009

BMI, body mass index; FEV1, Forced expiratory volume in first second; FVC, forced vital capacity.

The multivariable model was adjusted for age, sex, height, status of smoking, vigorous exercise (times/week), diabetes, and high-sensitivity C-reactive protein. BMI categories: normal (between 18.5 and 25 kg/m2), underweight (<18.5 kg/m2), and obese (≥25 kg/m2).