Fig. 3.

Regions of mNT with increased protection upon interaction with VDAC. Selected plots of deuterium incorporation into peptides from regions with significant increases in protection upon complex formation are shown. An additional plot is given (peptide 93 to 108) that is representative of a region with no significant change in deuterium incorporation upon complex formation. Regions that exhibit significant increases in HD-exchange protection are highlighted on the mNT crystal structure (PDB ID code 2QH7) in blue, while regions with similar protection factors are shown in beige.