Fig. 3.

Maternal viral infection alters microglia-enriched genes. Gene expression assessed in primary fetal microglia at (Left) 7 and (Right) 21 dpi. Target genes are highly enriched in microglia and involved in neurodevelopment, the microglia sensome, and inflammation. Results are expressed as average fold-change; n = 10 to 15 per sex per group per time point; an asterisk (*) indicates main effect of MIA, a dagger (†) indicates main effect of sex, and a double cross (‡) indicates MIA × sex interaction; and 3 symbols = P < 0.001, 2 symbols = P < 0.01, and 1 symbol = P < 0.05.