Table 1.
Relation between histopathological parameters and E-cadherin and Snail immunoexpression *G1: well differentiated CRC, G2: moderately differentiated CRC, G3: low differentiated CRC
|
Parameters |
Variables and number of cases (%) |
E-cadherin |
Snail |
||
|
% |
Score |
% |
Score |
||
|
Tumor stage |
I-6 (12.8%) II-14 (29.8%) III-14 (29.8%) IV-13 (27.7%) |
94.16+/-8.01 |
10 |
38.33+/-6.83 |
6.5 |
|
85.57+/-22.31 |
8.42 |
68.92+/-20.20 |
11 |
||
|
77.14+/-15.89 |
7.85 |
78.57+/-11.40 |
11.78 |
||
|
58.84+/-26.23 |
4.69 |
90.38+/-8.77 |
11.38 |
||
|
p=0.009 |
p=0.001 |
||||
|
Grading |
G1-8 (17.0%) G2-25 (53.2%) G3-14 (29.8%) |
88.75+/-20.83 |
8.25 |
40+/-20.87 |
7.5 |
|
80.2+/-19.22 |
8.04 |
74.6+/-19.36 |
11.4 |
||
|
61.78+/-25.54 |
5.85 |
87.5+/-9.14 |
11.5 |
||
|
p=0.170 |
p=0.005 |
||||
|
Vascular invasion |
Present-28 (59.6%) Absence-19 (40.4%) |
70.17+/-24.01 |
7.39 |
81.60+/-14.59 |
11.59 |
|
85+/- 19.57 |
7.47 |
59.21+/-27.29 |
9.68 |
||
|
p=0.038 |
p=0.047 |
||||
|
Perineural invasion |
Present-33 (70.2%) Absence-14 (29.8%) |
71.36+/-23.66 |
6.45 |
78.33+/-18.56 |
11.24 |
|
87.5+/-18.57 |
9.71 |
58.92+/-27.88 |
9.64 |
||
|
p=0.049 |
p=0.109 |
||||