Table 3.

Univariate And Multivariable Analysis Of Metabolites In Discriminating Patients With Chronic Obstructive Lung Disease From Normal Controls

Amino Acid (μM)	Univariate		Multivariable*
OR (95% CI)	p value	OR (95% CI)	p value
Histidine	0.98 (0.96–1.01)	0.160
Ornithine	1.01 (1.00–1.03)	0.117
Leucine	0.96 (0.94–0.97)	<0.001	0.95 (0.93–0.97)	<0.001
Phenylalanine	0.98 (0.95–1.01)	0.118
Hc	1.03 (1.00–1.05)	0.037
Oc	1.03 (1.01–1.04)	0.001	1.04 (1.02–1.06)	0.001
Pc	1.03 (1.00–1.06)	0.105

Note: *Multivariable analysis with forward selection model for all variables.

Abbreviations: OR, odds ratio; CI, confidence interval; Hc, corrected histidine; Oc, corrected ornithine; Pc, corrected phenylalanine.