Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Family pedigree based on a novel mutation in NOTCH3. (A) Family 4 I-2D: female, 35 years old, dead; II-2P (index patient 4, exon11 mutation/p.R607C): female, 39 years old; III-3: female, 22 years old. (B) Family 6 I-2D: female, 67 years old, dead; II-1: female, 62 years old; II-3P (index patient 6, exon20 mutation/p.R1100H): female, 52 years old. P – proband; D – dead.
