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. 2019 Aug 22;197(5):551–558. doi: 10.1007/s00408-019-00260-1

Table 2.

Occurrence of side effects among drug users

Coefficient Std. Error Z value P value
Nausea
 Intercept − 0.62 0.61 − 1.03 0.30
 Nintedanib 1.51 0.68 2.24 0.02*
 Pirfenidone 1.03 0.69 1.50 0.13
 Gender − 1.84 0.42 − 4.39  < 0.01*
Diarrhoea
 Intercept − 2.20 0.75 − 2.95  < 0.01*
 Nintedanib 2.41 0.78 3.10  < 0.01*
 Pirfenidone 0.39 0.82 0.48 0.64
Appetite lossa
 Intercept − 1.48 0.71 − 2.10 0.036*
 Nintedanib 2.34 0.72 3.24  < 0.01*
 Pirfenidone 2.50 0.73 3.42  < 0.01*
 Gender − 1.69 0.49 − 3.46  < 0.01*
 Antacid 0.92 0.38 2.42 0.016*
Weight lossa
 Intercept − 0.89 1.62 − 0.55 0.58
 Nintedanib 2.08 0.8 2.59  < 0.01*
 Pirfenidone 1.98 0.81 2.43 0.015*
 BMI − 0.11 0.05 − 2.09 0.036*
 Vit.D 0.8 0.36 2.24 0.025*
 Antacid 1.37 0.44 3.08  < 0.01*
Loss of taste or smell Perceptionb
 Intercept − 2.25 0.95 − 2.37 0.018*
 Nintedanib 0.32 0.66 0.48 0.63
 Pirfenidone 1.00 0.67 1.50 0.13
 Gender − 1.26 0.44 − 2.87  < 0.01*
 Time since diagnosis 0.46 0.26 1.75 0.080
 Antacid 1.06 0.46 2.3 0.021*

a1 observation deleted due to missing value

b10 observations deleted due to missing values

*Significant influence