Fig. 4.
SRF KO mice exhibit increase in spontaneous activity in the open field test. Mice individually explored the open field for 15 min. a Distance traveled in 15 min by WT and SRF KO mice n = 12 WT, n = 12 SRF KO female adult animals (t test, *p = 0.0484). b Mutant animals were significantly more active in all 3-min time bins in the open field (two-way repeated-measures ANOVA: genotype: F1,11 = 25.63, p = 0.0004, time: F4,44 = 21.28, p < 0.0001, genotype × time: F4,44 = 0.1032, p = 0.9808; followed by Sidak multiple-comparison post hoc test: *p < 0.05, **p < 0.01)