Table 1.
Patient characteristics at baseline and at 3 months of follow-up
| Characteristic | At baseline | At 3 months (visit 1) | Estimated mean difference (95% CI) | p value* |
|---|---|---|---|---|
| HbA1c (%) | 6.42 (0.68) | 6.12 (0.65) | − 0.30 (− 0.42 to − 0.18) | p < 0.0001 |
| Body weight (kg) | 93.81 (19.26) | 90.70 (19.12) | − 3.11 (− 4.04 to − 2.18) | p < 0.0001 |
| BMI (kg/m2) | 33.53 (6.90) | 32.39 (6.71) | − 1.14 (− 1.47 to − 0.81) | p < 0.0001 |
| Total daily insulin dose (units) | 43.31 (10.99) | 20.76 (6.60) | − 22.55 (24.96–20.14) | p < 0.0001 |
| Insulin requirement (IU/kg) | 0.47 (0.13) | 0.23 (0.08) | − 0.24 (− 0.27 to − 0.21) | p < 0.0001 |
| Metformin dose (mg/day) | 1500 [0–2000] | 2000 [1000–2000] | NA | p < 0.0001 |
Values are the mean (SD) or the median [IQR]
* From the Wilcoxon signed-rank test for metformin dose and the paired t test for other parameters