. Author manuscript; available in PMC: 2020 Feb 1.

Published in final edited form as: Psychopharmacology (Berl). 2018 Nov 17;236(2):821–830. doi: 10.1007/s00213-018-5118-y

Table 1.

Effect of chronic LY379268 (10 mg/kg) on the interaction between LY379268 (3 mg/kg) and PCP (5 mg/kg) in the Behavioral Pattern Monitor.

Chronic Treatment	Acute Treatment	Distance traveled (60 min)	Rearings (60 min)	Pokes (60 min)
Vehicle	VEH - VEH	21172.1 ± 1551.7	294.1 ± 26.2	258.8 ± 19.4
	VEH - PCP	35595.1 ± 2678.0^**	121.7 ± 24.0^**	210.1 ± 13.2
	LY - VEH	21006.1 ± 2195.4	278.9 ± 29.2	194.0 ± 25.1
	LY - PCP	25181.1 ± 2763.3^#	50.3 ± 23.3^**	141.5 ± 23.8^**

LY379268	VEH - VEH	20497.4 ± 1436.7	405.1 ± 14.1	245.3 ± 23.6
	VEH - PCP	35445.1 ± 2344.0^**	177.9 ± 27.7^**	228.0 ± 23.9
	LY - VEH	20402.9 ± 1557.8	286.1 ± 29.2^*	199.9 ± 25.7
	LY - PCP	27495.1 ± 3070.0	138.7 ± 30.2^**	173.6 ± 6.0

Data are shown as group means

^±

SEM.

p<0.05 compared to VEH –PCP.

p<0.05

^**

p<0.01 compared to VEH-VEH.