Figure 2.
Delphinidin regulates the level of HOX transcript antisense RNA (HOTAIR) in breast tissues of different groups. A, The levels of HOTAIR in breast cancer tissues were detected by qRT‐PCR; ## P < .01 compared with the control group. B, The levels of HOTAIR in breast cancer cells MDA‐MB‐231(M231), MCF‐7 (M7), MDA‐MB‐453(M453) transfected with blank plasmids (mock control, MC) or transfected with pcDNA‐HOTAIR(TCHOTAIR) were detected by qRT‐PCR. **P < .01 compared with MC. C, Cell viability was determined by CCK‐8 assay in breast cancer cells and TCHOTAIR with or without delphinidin (40 μmol/L) treatment. D, Wound healing assay in breast cancer cells and TCHOTAIR with or without delphinidin treatment. E, Transwell invasion assay in breast cancer cells and TCHOTAIR with or without delphinidin treatment. F, Transwell migration assay in breast cancer cells and TCHOTAIR with or without delphinidin treatment. The data are presented as the means ± SD (n = 3). *P < .05 and **P < .01 compared with Control