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. 2019 Aug 29;110(10):3038–3048. doi: 10.1111/cas.14161

Figure 5.

Figure 5

Significant correlations between immune characteristics and clinicopathological features of patients with retroperitoneal liposarcoma. A, CD4+ tumor‐infiltrating lymphocytes (TILs) decreased in relapsed tumors (P = .024). B,C, Higher proportions of CD20+ TILs were detected in patients with (B) single tumor (P = .004) or (C) without tumor necrosis (P = .002). D, Patients with grade 2 tumors had the lowest proportion of programmed cell death‐1 (PD‐1)+ TILs (P = .014). (E) CD4+ (P = .043), (F) CD8+ (P = .018), and (G) CD20+ TILs were negatively correlated with tumor size (P = .023). H‐J, Expression of PD‐1 ligand‐1 (PD‐L1) markedly decreased in patients with (H) multiple tumors (P = .035), (I) necrotic tumors (P = .026), or (J) G3 tumors (P = .006). K, Similar to PD‐L1, PD‐1 expression in tumor cells decreased in patients with multiple tumors compared to those with single tumors (P = .014)