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Representative case of non‐small cell lung cancer with altered tumor microenvironment and response to epidermal growth factor receptor‐tyrosine kinase inhibitor EGFR‐TKI) before and after developing acquired resistance to the initial EGFR‐TKI therapy. AF, allele frequency; ddPCR, droplet digital PCR; PD, progressive disease; PD‐L1/2, programmed cell death‐1 ligand‐1/2; TIL, tumor‐infiltrating lymphocyte; TPS, tumor proportion score
