Figure 2.

Correlation between heat shock protein 105 (HSP105)‐specific CTL frequencies and clinical outcomes. A, Spider plot of tumor size changes during HSP105 peptide vaccination. CTL(+) and CTL(−) indicate patients with and without the induction of HSP105‐specific CTLs, respectively, in ex vivo and in vitro γ‐interferon enzyme‐linked immunospot assays. B, Negative correlation observed between maximum numbers of HSP105‐specific CTL spots and the tumor increase ratio per day calculated by dividing tumor increase values by the number of observation days (r = −0.501, P < .01). C, Correlation between HSP105‐specific CTL frequency and overall survival (OS) (r = 0.706, P < .01)