GUCY2C protein is expressed in projection sites of dopaminergic midbrain neurons. GUCY2C protein expression in the Caudoputamen (a1), nucleus Accumbens (a2), lateral hypothalamic area (b1), nigrostriatal tract (b1), and lateral part of the central amygdalar nucleus (CeL) (b2) co-localized with TH. CPu: Caudoputamen; Acb: nucleus Accumbens; OT: Olfactory Tubercle; ns: nigrostriatal tract; LHA: Lateral Hypothalamic Area; CeL: Lateral part of the Central amygdalar nucleus. Scale bars: 500 μm (a) and (b), or 50 μm (insets).