Table 3.
Comparison of seropositive and seronegative patients for RF and anti-CCP.
| Variable | RF or anti-CCP | P value | |
|---|---|---|---|
| Gender | Seronegative | Seropositive | |
| Male | 31 | 65 | <0.05 |
| Female | 123 | 293 | <0.05 |
|
| |||
| Comorbidity | Seronegative | Seropositive | |
| Diabetes | 50 | 109 | <0.05 |
| Hypertension | 51 | 140 | <0.05 |
| Thyroid disease | 35 | 85 | <0.05 |
| Cancer | 7 | 26 | <0.05 |
| Dyslipidemia | 63 | 153 | <0.05 |
| CAD | 26 | 69 | <0.05 |
| CKD | 8 | 28 | <0.05 |
| Osteoporosis | 14 | 55 | <0.05 |
| Gastro-intestinal | 46 | 99 | <0.05 |
| Iron deficiency anemia | 34 | 77 | <0.05 |
| Thalassemia | 7 | 14 | >0.05 |
| Sickle cell anemia | 0 | 2 | >0.05 |
| G6PD | 6 | 15 | >0.05 |
| Asthma | 22 | 37 | >0.05 |
| COPD | 1 | 11 | <0.05 |
| Migraine | 11 | 14 | >0.05 |
| Depression | 9 | 18 | >0.05 |
|
| |||
| Erosion on X-ray | Seronegative | Seropositive | |
| No | 107 | 284 | <0.05 |
| Yes | 47 | 74 | <0.05 |
|
| |||
| Weight Class (BMI) | Seronegative | Seropositive | |
| Normal | 26 | 71 | <0.05 |
| Obese | 79 | 191 | <0.05 |
| Overweight | 45 | 92 | <0.05 |
| Underweight | 4 | 4 | >0.05 |
BMI, body mass index; CAD, coronary artery disease; CCP, citrullinated peptide; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; G6PD, glucose-6-phosphate dehydrogenase; RF, rheumatoid factor.