Differentially expressed exons (DEEs) after ethanol and Ro 25–6981 treatment. C57BL/6 male mice were treated (45 minutes) with vehicle (saline, n=8), ethanol (ETOH, 2.4 g/kg, n=7), or Ro 25–6981 (10 mg/kg, n=8). RNA-Seq and DEE analysis (DEXSeq) were performed using RNA isolated from hippocampal synaptoneurosomes. (A) Venn diagram comparing DEEs in ethanol- and Ro 25–6981-treatment groups identified 1609 overlapping exons (p ≤ 0.0001). (B) The top five molecular function gene ontologies (GOs) for the overlapping DEEs are shown.