Table 4.
Condition and Receptor fIPSC |
Q (pA*ms) |
D37 (ms) |
Peak (pA) |
n
(Cells) |
Mice |
Control GABA | 2231 ± 433 | 93.4 ± 15 | 25.1 ± 4.7 | 12 | 6 |
Diabetic GABA | 1710 ± 238 | 36.2 ± 10.7† | 38.2 ± 5.2 | 13 | 5 |
Control GABAAR | 692.8 ± 156.7 | 44.4 ± 9.5 | 11.3 ± 1.3 | 13 | 6 |
Diabetic GABAAR | 327.5 ± 45.6† | 7.9 ± 1.8† | 11.9 ± 2.6 | 11 | 5 |
Control GABACR | 1249 ± 182 | 97.4 ± 13.9 | 13.8 ± 1.0 | 12 | 6 |
Diabetic GABACR | 964 ± 170 | 19.6 ± 4.9‡ | 29.4 ± 5.8* | 9 | 5 |
Average values of fIPSC charge transfer (Q), D37 and peak amplitude for rod bipolar cell GABAAR and GABACRs are shown.
P ≤ 0.05 when compared with values recorded in control cells (t-test).
P ≤ 0.01 when compared with values recorded in control cells (t-test).
P < 0.0001 when compared with values recorded in control cells (t-test).