Table 5.
Values for GABA Release at the A17 Amacrine Cell to Rod Bipolar Cell Synapse
Condition |
Vesicles |
D37 (ms) |
Peak |
n
(Cells) |
Mice |
Control GABAAR | 72 ± 16.4 | 89.8 ± 12.8 | 0.65 ± 0.12 | 13 | 6 |
Diabetic GABAAR | 4 ± 0.6† | 53.6 ± 10.1* | 0.05 ± 0.008† | 11 | 5 |
Control GABACR | 8 ± 1.7 | 115 ± 29 | 0.10 ± 0.01 | 12 | 6 |
Diabetic GABACR | 8 ± 1.4 | 33.1 ± 8.6* | 0.11 ± 0.02 | 9 | 5 |
Average values of the amount (vesicles), timing and peak of GABA release from A17 amacrine cells determined by deconvolution analysis are shown.
P < 0.05 when compared with control GABA release values (t-test).
P < 0.01 when compared with control GABA release values (t-test).