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(A–C) Representative ERG waveforms for rod, mixed, and cone conditions. Black arrows indicate the timing of the stimulation. The averaged amplitudes were shown for rod b-wave (D), mixed a-wave (E), mixed b-wave (F), and cone b-wave (G) (n = 5–6). Note that most of decreased amplitudes were suppressed by topotecan administration. Error bars indicate the standard error. *p < 0.05, **p < 0.01, Mann–Whitney’s U test.
