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. 2019 Sep 26;13:1033. doi: 10.3389/fnins.2019.01033

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Copyright © 2019 Balashova, Pershin, Zaborskaya, Tkachenko, Mironov, Guryev, Kurbatov, Gainullin and Mukhina.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Upstream regulators identified by Ingenuity Pathway analysis for hyaluronidase dependent treatment. Positive activation Z-score (>2) indicates activation of these upstream regulators. CREB1, cAMP response element-binding protein; FGF2, fibroblast growth factor 2; TICAM1, TIR domain-containing adaptor molecule 1; MTPN, myotrophin; TGFB, Transforming growth factor beta.