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. 2019 Aug 5;101(4):828–836. doi: 10.4269/ajtmh.19-0024

Table 4.

Sensitivity and specificity of syndromic diagnoses for STIs and urogenital schistosomiasis

CT/NG TV S. haematobium
NAAT+ NAAT− Total NAAT+ NAAT− Total Urine+ Urine− Total
Symptomatic 4 75 79 16 65 81 11 72 83
Asymptomatic 12 260 272 36 240 276 53 231 284
Total 16 335 351 52 305 357 64 303 367
Sensitivity (4/16) = 25% (16/52) = 31% (11/64) = 17%
Specificity (260/335) = 78% (240/305) = 79% (231/303) = 76%

CT/NG = chlamydia or gonorrhea (Chlamydia trachomatis or Neisseria gonorrhoeae); NAAT = nucleic acid amplification test; STI = sexually transmitted infection; TV = trichomoniasis (Trichomonas vaginalis). For each infection of interest, syndromic recognition (defined as the presence of any urogenital symptom in patient reports) was compared against the appropriate gold standard laboratory test: NAAT for STIs and urine microscopy for schistosomiasis.