Table 3.
Characteristics of matched pairs of hepatitis C virus (HCV)–seronegative recipients versus HCV-seropositive recipients of HCV-viremic kidneys
| Variable | Patient D+/R−, n=102a | Matched Comparator D+/R+, n=204 | All Potential Comparators D+/R+, n=701 | Standard Difference in Means before Match | Standard Difference in Means after Match |
|---|---|---|---|---|---|
| Recipient variables | |||||
| Age at transplant, yr, mean (SD) | 58.8 (8.8) | 58.9 (8.2) | 59.9 (7.9) | −0.1303 | −0.0084 |
| Sex (women) | 24 (23.5%) | 48 (23.5%) | 162 (23.1%) | 0.0016 | 0 |
| Race (black) | 47 (46.1%) | 94 (46.1%) | 413 (58.9%) | −0.1323 | 0 |
| Cause of ESKD | |||||
| Diabetes | 43 (42.1%) | 86 (42.1%) | 291 (41.5%) | 0.0018 | 0 |
| Hypertension | 16 (15.7%) | 32 (15.7%) | 222 (31.6%) | −0.1604 | 0 |
| GN | 11 (10.8%) | 22 (10.8%) | 27 (3.9%) | 0.0682 | 0 |
| Cystic | 10 (9.8%) | 20 (9.8%) | 21 (3%) | 0.0768 | 0 |
| Other | 22 (21.6%) | 44 (21.6%) | 140 (20%) | 0.0136 | 0 |
| Prior transplant | 14 (13.7%) | 28 (13.7%) | 139 (19.8%) | −0.0626 | 0 |
| Prior malignancy | 5 (4.9%) | 10 (4.9%) | 83 (11.8%) | −0.07 | 0 |
| Blood type | |||||
| A | 27 (26.5%) | 54 (26.5%) | 205 (29.2%) | −0.0196 | 0 |
| B | 17 (16.7%) | 34 (16.7%) | 113 (16.1%) | 0.0036 | 0 |
| O | 56 (54.9%) | 112 (54.9%) | 360 (51.4%) | 0.0294 | 0 |
| AB | 2 (1.9%) | 4 (1.9%) | 23 (3.3%) | −0.0134 | 0 |
| Duration on dialysis | |||||
| Preemptive | 16 (15.7%) | 32 (15.7%) | 87 (12.4%) | 0.0311 | 0 |
| <1 yr | 27 (26.5%) | 54 (26.5%) | 102 (14.6%) | 0.1261 | 0 |
| 1–5 yr | 49 (48%) | 98 (48%) | 397 (56.7%) | −0.0914 | 0 |
| >5 yr | 10 (9.8%) | 20 (9.8%) | 114 (16.3%) | −0.0658 | 0 |
| Insurance type | |||||
| Private | 36 (35.3%) | 72 (35.3%) | 185 (26.4%) | 0.0852 | 0 |
| Medicaid | 9 (8.8%) | 18 (8.8%) | 58 (8.3%) | 0.0142 | 0 |
| Medicare/other | 57 (55.9%) | 114 (55.9%) | 458 (65.3%) | −0.0995 | 0 |
| PRA (mean) | 9.4 (23.4) | 9.4 (23.5) | 15.2 (28.5) | −0.2276 | −0.0011 |
| Education level | |||||
| Less than high school | 1 (1%) | 2 (1%) | 36 (5.1%) | −0.0417 | 0 |
| High school and college | 67 (65.7%) | 134 (65.7%) | 515 (73.5%) | −0.0755 | 0 |
| Bachelor and higher | 32 (31.4%) | 64 (31.4%) | 134 (19.1%) | 0.1193 | 0 |
| Unknown | 2 (1.9%) | 4 (1.9%) | 16 (2.3%) | −0.002 | 0 |
| Donor variablesb | |||||
| Allocation KDPI %, mean (SD)c | 47 (14.6) | 47 (16.3) | 48 (16.7) | −0.0155 | 0 |
PRA, panel reactive antibody; KDPI, kidney donor profile index.
a
We were unable to find optimal matches for one of 103 patients.
b
Donors with a history of diabetes were excluded from the match, because none of the HCV-viremic kidney transplant recipients received a kidney from a donor with history of diabetes.
c
Postmatch characteristics of the individual elements of KDPI are presented in Supplemental Table 6.