Figure 3.

Architectures of genomic loci for the representative subtypes of CRISPR-Cas systems associated with RTs. Group-II intron-like RTs (ancient, clades 2–13; and recent, clade 1), Retron RT-like (clade 14) and Abi-P2 RT-like (clade 15). For each locus, the node number (Fusicatenibacter saccharivorans was not included in the 9,141 entries), species, respective nucleotide coordinates and CRISPR-Cas system subtype (derived from the respective effector genes) are indicated. Genes are shown roughly to scale; CRISPR arrays are indicated in brackets and are not to scale. The genes within each locus are denoted as in Supplementary Table 3. Homologous genes are colour-coded, with the exception of most of the ancillary genes, which are shown in white; unknown proteins are shown in grey.