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. 2019 Sep 28;10(1):425–436. doi: 10.1080/21655979.2019.1669518

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© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Knockdown of STIM1 expression induced cell cycle block in NSCLC cells. The cell cycle distribution was investigated in A549 and SK-MES-1 cells with STIM1 knockdown and it was observed that the S and G2/M phase population was markedly increased, while the G0/G1 phase population was significantly decreased compared with their controls. (a) Flow cytometric assay for A549 cells. (b) Flow cytometric assay for SK-MES-1 cells. *p < 0.05 by Student’s t-test. STIM1, stromal interaction molecule 1.