TABLE 2.
Predicted enzymes and genes for tRNATrp nucleoside modificationsa
| Modified nucleoside and position | Enzyme(s) or RNA | Predicted gene ID |
|---|---|---|
| Cm6 | Unknown | Unknown |
| s4U8 | ThiI | Tk0366 |
| m22G10 | Archaeal Trm11 | Tk0981 |
| Ψ13 | TruD | Tk2302 |
| G+15 | ArcTGT, ArcS | Tk0760, Tk2156 |
| s2C17 | Unknown | Unknown |
| Um20 | L7Ae, Nop5, archaeal fibrillarin, C/D-box guide RNA | Tk1311, Tk0184, Tk0183, RNA |
| Ψ22 | Unknown | Unknown |
| m5Cm32 | Unknown methyltransferase, archaeal TrmJ | Unknown, Tk1970 |
| Cm34 | L7Ae, Nop5, archaeal fibrillarin, intron (C/D-box guide RNA) | Tk1311, Tk0184, Tk0183, intron |
| mimG37 | Trm5b, TYW1, TYW3, Trm5a | Tk0497, Tk1671, Tk0175, Tk2223 |
| Cm39 | L7Ae, Nop5, archaeal fibrillarin, intron (C/D-box guide RNA) | Tk1311, Tk0184, Tk0183, intron |
| Gm42 | L7Ae, Nop5, archaeal fibrillarin, C/D-box guide RNA | Tk1311, Tk0184, Tk0183, RNA |
| m5C48 | Archaeal Trm4 | Tk0360 |
| m5C49 | Archaeal Trm4 | Tk0360 |
| m5s2U54 | RumA, TtuA?, TtuB?, α | Tk2134, Tk1556?, Tk1093?, α |
| Ψ55 | Pus10 or archaeal Cbf5 | Tk0903 or Tk1509 |
| Cm56 | Trm56 | Tk0060 |
| m1I57 | Archaeal TrmI, unknown deaminase | Tk1328, unknown |
| m1A58 | Archaeal TrmI | Tk1328 |
| m2G67 | Trm14 | Tk1863 |
a
?, enzymatic activity of the protein has not been confirmed in archaea.