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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Alcohol Clin Exp Res. 2019 Aug 26;43(10):2153–2166. doi: 10.1111/acer.14170

Figure 6. Prolonged low-frequency stimulation induced long-term depression is unaffected by prenatal ethanol exposure.

Figure 6.

(A) Average long-term depression (LTD) recordings from the beginning of baseline to the end of the post-conditioning recording. Dots represent the average percentage of change in the field excitatory postsynaptic potential (fEPSP) slope relative to baseline and the error bars represent the SEM. (B) LTD was measured as the average percentage of change in the fEPSP slope relative to baseline for minutes 55-60 following delivery of the LFS (1800×1Hz; indicated as black bar in A). The magnitude of LTD was reduced only in male offspring following PNEE. Bars represent the average percentage of change in the fEPSP slope for LTD (C) with points representing the average STD and LTD for each individual slice in this dataset. Experimental n: LTDControl Female: −36.64 ± 5.44 %; n = 14 slices, 6 animals, 4 litters; LTDPNEE Female: −28.83 ± 5.67 %; n = 7 slices, 5 animals, 3 litters; LTDControl Male: −36.82 ± 5.12 %; %; n = 8 slices, 4 animals, 2 litters; LTDPNEE Male: −32.66 ± 6.86 %; n = 5 slices, 3 animals, 3 litters. * p < 0.05.