Table 2.
Univariable And Multivariable Analyses For PHLF
| Variable | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|
| OR (95% CI) | P Value | OR (95% CI) | P Value | |
| Age (≥60 years) | 1.450 (0.934–2.252) | 0.098 | 1.054 (0.902–2.059) | 0.118 |
| Sex (female) | 0.345 (0.165–0.721) | 0.005 | 0.332 (0.149–0.737) | 0.007 |
| AFP (≥400 ng/mL) | 1.005 (0.708–1.427) | 0.976 | – | – |
| CSPH | 5.208 (3.614–7.505) | < 0.001 | 3.573 (2.298–5.556) | < 0.001 |
| C-P score | 2.102 (1.647–2.681) | < 0.001 | 0.940 (0.665–1.329) | 0.726 |
| ALBI score | 8.501 (5.244–13.781) | < 0.001 | 5.280 (2.763–10.086) | < 0.001 |
| APRI score | 2.156 (1.777–2.617) | < 0.001 | 1.583 (1.275–1.964) | < 0.001 |
| Tumor size (cm) | 1.069 (1.025–1.114) | 0.002 | 0.989 (0.934–1.047) | 0.696 |
| Tumor number (≥3) | 1.438 (0.889–2.327) | 0.139 | - | - |
| Major liver resection | 2.566 (1.769–3.722) | < 0.001 | 2.986 (1.845–4.835) | < 0.001 |
| Blood loss (>400 mL) | 3.423 (2.404–4.874) | < 0.001 | 2.294 (1.503–3.502) | < 0.001 |
Abbreviations: AFP, alpha fetoprotein; CSPH, clinically significant portal hypertension; C-P, Child-Pugh; ALBI, albumin–bilirubin; APRI, aspartate aminotransferase to platelet ratio index; PHLF, post- hepatectomy liver failure.