Table 2. Patient characteristics of p53 signature-positive and negative groups.
| Characteristics | p53 signature | p value | ||
|---|---|---|---|---|
| Positive (n=21) | Negative (n=92) | |||
| Age (yr) | 47 (35–75) | 41 (23–80) | 0.003* | |
| BMI (kg/m2) | 24.2±4.2 | 22.7±3.3 | 0.076† | |
| Post-menopausal | 7 (33) | 11 (12) | 0.041‡ | |
| Referral screening tool (positive) | 0 (0) | 1 (1) | 1.000‡ | |
| Current smoker (yes) | 5 (24) | 15 (16) | 0.526‡ | |
| Parity | 0.003‡ | |||
| 0 | 10 (48) | 13 (14) | ||
| 1 | 2 (10) | 9 (10) | ||
| ≥2 | 9 (43) | 70 (76) | ||
| Parous women (parity≥1) | 11 (53) | 79 (86) | 0.002‡ | |
| Surgical indication | 0.001‡ | |||
| Gynecological | 19 (90) | 48 (53) | ||
| Obstetric | 2 (10) | 44 (47) | ||
Non-normally distributed variables are expressed as the median (range). Normally distributed variables are expressed as the mean±SD. Categorical variables are expressed as number (%). BMI and current smoking status in obstetric patients indicate patient's status before current pregnancy. Parity includes current delivery in obstetric patients. Total percentage of parity in p53-positive group was not 100% due to rounding to the first decimal place.
BMI, body mass index.
*Mann-Whitney U test; †Student's t-test; ‡Fisher's exact test.