Table 2.

Treatment-related adverse events. LVEF: left ventricle ejection fraction. HTA: hypertension

Adverse events	Grade I		Grade II		Grade III		Grade IV
	n	%	n	%	n	%	n	%
LVEF reduction	0	0	2	4.4	0	0	0	0
HTA	1	2.2	1	2.2	0	0	0	0
Heart failure	0	0	0	0	1	2.2	0	0
Hand–foot syndrome	5	11.1	0	0	1	2.2	0	0
Fatigue	13	28.9	13	28.9	6	13.3	1	2.2
Diarrhoea	4	8.9	8	17.8	11	24.4	1	2.2
Nausea	4	8.9	8	17.8	8	17.8	1	2.2
Vomiting	8	17.8	3	6.7	6	13.3	0	0
Mucositis	2	4.4	3	6.7	1	2.2	0	0
Hyporexia	4	8.9	1	2.2	1	2.2	0	0
Anaemia	11	24.4	5	11.1	1	2.2	0	0
Neutropenia	3	6,7	6	13.3	1	2.2	0	0
Thrombocytopenia	7	15.5	5	11.1	0	0	0	0
Neurotoxicity	22	48.8	12	26.6	1	2.2	0	0