Table 1.
Assays of bovine tuberculin PPDs in naturally TB-infected cattle: 2010–2017, PPDs used in the Irish programme; 2006, 2010, and 2018, INBS and BIS; 2004, 2008, trials involving PPDs in tuberculin testing.
Batch no. | Year manufacture | Protein content mg/ml | Guinea-pig assay IU/ml | Bovine assay IU/ml | ||||
---|---|---|---|---|---|---|---|---|
Year | 95% confidence limits | Standard | ||||||
Potency* | Potency | Lower | Upper | |||||
INBS | 1994 | 1.0 | 33,700 | 2018 | 30,568 | 19,749 | 46,981 | BIS |
BIS | 1979 | 1.0 | 32,500 | 2013 | 25,821 | 13,792 | 46,561 | INBS |
INBS | 1994 | 1.0 | 33,700 | 2006 | 46,079 | 31,722 | 68,238 | BIS |
170312 | 2017 | 1.0 | 30,350 | 2017 | 39,098 | 23,359 | 66,470 | INBS |
171502 | 2017 | 1.2 | 23,380 | 2017 | 76,927 | 46,043 | 140,170 | INBS |
162408 | 2016 | 0.95 | 24,850 | 2017 | 35,961 | 23,595 | 55,056 | INBS |
161102 | 2016 | 1.42 | 24,210 | 2016 | 50,082 | 30,243 | 86,391 | INBS |
153501 | 2015 | 1.25 | 40,950 | 2016 | 70,250 | 42,339 | 125,726 | INBS |
143806 | 2014 | 1.04 | 31,140 | 2015 | 59,058 | 36,584 | 100,423 | INBS |
143813 | 2014 | 1.02 | 30,540 | 2015 | 58,424 | 37,698 | 94,453 | INBS |
141310 | 2014 | 1.02 | 30,940 | 2015 | 52,697 | 34,020 | 84,478 | INBS |
141304 | 2014 | 1.01 | 30,640 | 2014 | 59,062 | 30,037 | 129,421 | INBS |
134511 | 2013 | 1.04 | 27,950 | 2014 | 36,822 | 18,300 | 75,367 | INBS |
102401 | 2010 | 1.11 | 26,580 | 2014 | 59,062 | 30,037 | 129,421 | INBS |
132203 | 2013 | 1.24 | 30,880 | 2013 | 52,601 | 35,380 | 80,416 | INBS |
132206 | 2013 | 1.08 | 26,900 | 2013 | 37,054 | 24,837 | 55,611 | INBS |
120103 | 2012 | 1.32 | 24,280 | 2012 | 64,795 | 37,264 | 122,280 | INBS |
120101 | 2012 | 1.15 | 21,130 | 2012 | 47,772 | 27,908 | 85,194 | INBS |
110404 | 2011 | 1.33 | 21,880 | 2011 | 50,811 | 30,532 | 88,291 | INBS |
110404 | 2011 | 1.33 | 21,880 | 2012 | 81,239 | 33,751 | 266,063 | INBS |
112006 | 2011 | 1.24 | 24,060 | 2012 | 59,999 | 35,112 | 109,705 | INBS |
104012 | 2010 | 1.16 | 23,500 | 2011 | 38,738 | 23,128 | 65,840 | INBS |
100308 | 2010 | 1.38 | 26,200 | 2011 | 57,979 | 34,854 | 102,114 | INBS |
102414 | 2010 | 1.11 | 26,220 | 2011 | 41,509 | 21,299 | 83,991 | INBS |
LPa | 2008 | 0.16 | 3,400 | 2008 | 11,920 | 4,950 | 23,540 | INBS |
NPa | 2008 | 1.23 | 26,380 | 2008 | 61,840 | 31,570 | 136,000 | INBS |
HPa | 2008 | 3.11 | 66,700 | 2008 | 125,540 | 62,570 | 323,820 | INBS |
JNb | 2004 | na | 10,250 | 2005 | 11,552 | 6,202 | 20,779 | INBS |
FMb | 2004 | na | 16,500 | 2005 | 25,900 | 14,866 | 44,784 | INBS |
KSb | 2004 | na | 9,250 | 2005 | 28,747 | 16,535 | 49,754 | INBS |
HTb | 2004 | na | 31,500 | 2005 | 33,868 | 19,532 | 58,734 | INBS |
GRb | 2004 | na | 27,750 | 2005 | 45,003 | 25,217 | 81,062 | INBS |
LPb | 2004 | na | 24,500 | 2005 | 45,003 | 25,217 | 81,062 | INBS |