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. 2019 Oct 1;10:2330. doi: 10.3389/fimmu.2019.02330

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Copyright © 2019 Demeyer, Van Nuffel, Baudelet, Driege, Kreike, Muyllaert, Staal and Beyaert.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Malt1-KO mice do not develop multi-organ inflammation. (A) H&E staining (scale bar 100 μm) of several organs from WT and Malt1-KO mice (Malt1-KO mice had skin lesions and the WT and KO mice were between 30 and 40 weeks old). (B) Blood glucose levels in mice of ±20 weeks (left, WT: n = 5 and KO: n = 4) and mice of 7–8 months (right, WT: n = 10 and KO: n = 8). Open circles (WT), gray squares (KO), and black squares (KO + AD = KO mice with atopic dermatitis) represent individual mice. The mean ± SEM is indicated on the graphs. The statistical significance between groups was calculated with an unpaired 2-tailed Student's t-test: no significant difference was found.