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. 2019 Oct 1;10:2155. doi: 10.3389/fmicb.2019.02155

FIGURE 3.

FIGURE 3

The effect of A. muciniphila and its EVs on mRNA expression of genes in epidydimal adipose tissue in C57bl/6 mice. Relative mRNA expression of (A) PPAR-γ, (B) PPAR-α, (C) TGF-β, (D) TLR-4, (E) TNF-α, and (F) IL-6. Data are normalized using HPRT as control gene. P < 0.05 and ∗∗P < 0.01 were considered statistically significant, respectively. ND, normal diet + PBS; NA.m, normal diet + A. muciniphila (109 CFU); NEV, normal diet + EVs (10 μg protein); HFD, high-fat diet + PBS; HA.m, high-fat diet + A. muciniphila (109 CFU); HEV, high-fat diet + EVs (10 μg protein).